Carbonic anhydrase inhibitory properties of some uracil derivatives

Inhibitors of carbonic anhydrase (CA) have been carried out in many therapeutic applications, especially antiglaucoma activity. In this study, we investigated some uracil derivatives (4–12) to inhibit human CA I (hCA I) and II (hCA II) isoenzymes. The K(I) values of the compounds 4–12 are in the ran...

Descripción completa

Detalles Bibliográficos
Autores principales: Alper Türkoğlu, Emir, Şentürk, Murat, Supuran, Claudiu T., Ekinci, Deniz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009904/
https://www.ncbi.nlm.nih.gov/pubmed/28097897
http://dx.doi.org/10.1080/14756366.2016.1235043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009904/
https://www.ncbi.nlm.nih.gov/pubmed/28097897
http://dx.doi.org/10.1080/14756366.2016.1235043

Ejemplares similares