Inhibition of human cytochromes P450 2A6 and 2A13 by flavonoids, acetylenic thiophenes and sesquiterpene lactones from Pluchea indica and Vernonia cinerea

The human liver cytochrome P450 (CYP) 2A6 and the respiratory CYP2A13 enzymes play role in nicotine metabolism and activation of tobacco-specific nitrosamine carcinogens. Inhibition of both enzymes could offer a strategy for smoking abstinence and decreased risks of respiratory diseases and lung can...

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Detalles Bibliográficos
Autores principales: Boonruang, Supattra, Prakobsri, Khanistha, Pouyfung, Phisit, Srisook, Ekaruth, Prasopthum, Aruna, Rongnoparut, Pornpimol, Sarapusit, Songklod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009911/
https://www.ncbi.nlm.nih.gov/pubmed/28856944
http://dx.doi.org/10.1080/14756366.2017.1363741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009911/
https://www.ncbi.nlm.nih.gov/pubmed/28856944
http://dx.doi.org/10.1080/14756366.2017.1363741

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