Investigation of piperazines as human carbonic anhydrase I, II, IV and VII activators

Four human (h) carbonic anhydrase isoforms (CA, EC 4.2.1.1), hCA I, II, IV, and VII, were investigated for their activation profile with piperazines belonging to various classes, such as N-aryl-, N-alkyl-, N-acyl-piperazines as well as 2,4-disubstituted derivatives. As the activation mechanism invol...

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Detalles Bibliográficos
Autores principales: Angeli, Andrea, Chiaramonte, Niccolò, Manetti, Dina, Romanelli, Maria Novella, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009915/
https://www.ncbi.nlm.nih.gov/pubmed/29280407
http://dx.doi.org/10.1080/14756366.2017.1417277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009915/
https://www.ncbi.nlm.nih.gov/pubmed/29280407
http://dx.doi.org/10.1080/14756366.2017.1417277

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