Cargando…

Investigation of piperazines as human carbonic anhydrase I, II, IV and VII activators

Four human (h) carbonic anhydrase isoforms (CA, EC 4.2.1.1), hCA I, II, IV, and VII, were investigated for their activation profile with piperazines belonging to various classes, such as N-aryl-, N-alkyl-, N-acyl-piperazines as well as 2,4-disubstituted derivatives. As the activation mechanism invol...

Descripción completa

Detalles Bibliográficos
Autores principales:	Angeli, Andrea, Chiaramonte, Niccolò, Manetti, Dina, Romanelli, Maria Novella, Supuran, Claudiu T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2017
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009915/ https://www.ncbi.nlm.nih.gov/pubmed/29280407 http://dx.doi.org/10.1080/14756366.2017.1417277

Ejemplares similares

Amino Acids as Building Blocks for Carbonic Anhydrase Inhibitors
por: Chiaramonte, Niccolò, et al.
Publicado: (2018)

New Histamine-Related Five-Membered N-Heterocycle Derivatives as Carbonic Anhydrase I Activators
por: Chiaramonte, Niccolò, et al.
Publicado: (2022)

Benzamide-4-Sulfonamides Are Effective Human Carbonic Anhydrase I, II, VII, and IX Inhibitors
por: Abdoli, Morteza, et al.
Publicado: (2018)

Discovery of novel 1,3-diaryltriazene sulfonamides as carbonic anhydrase I, II, VII, and IX inhibitors
por: Akocak, Suleyman, et al.
Publicado: (2018)

Synthesis and carbonic anhydrase activating properties of a series of 2-amino-imidazolines structurally related to clonidine(1)
por: Chiaramonte, Niccolò, et al.
Publicado: (2020)

Synthesis and biological evaluation of histamine Schiff bases as carbonic anhydrase I, II, IV, VII, and IX activators
por: Akocak, Suleyman, et al.
Publicado: (2017)

Carbonic Anhydrase IV Selective Inhibitors Counteract the Development of Colitis-Associated Visceral Pain in Rats
por: Lucarini, Elena, et al.
Publicado: (2021)

Five-Membered Heterocyclic Sulfonamides as Carbonic Anhydrase Inhibitors
por: Angeli, Andrea, et al.
Publicado: (2023)

Investigation on Hydrazonobenzenesulfonamides as Human Carbonic Anhydrase I, II, IX and XII Inhibitors
por: Moi, Davide, et al.
Publicado: (2022)

Activation of human α-carbonic anhydrase isoforms I, II, IV and VII with bis-histamine schiff bases and bis-spinaceamine substituted derivatives
por: Akocak, Suleyman, et al.
Publicado: (2019)

Carbonic Anhydrase Inhibitors. Part 46(1) Inhibition of Carbonic Anhydrase Isozymes I, II and IV With Trifluoromethylsulfonamide Derivatives and Their Zinc(II) and Copper(II) Complexes
por: Mincione, Giovanna, et al.
Publicado: (1997)

Synthesis and Biological Evaluation of Imidazo[2,1-b]Thiazole based Sulfonyl Piperazines as Novel Carbonic Anhydrase II Inhibitors
por: Manasa, Kesari Lakshmi, et al.
Publicado: (2020)

Synthesis and carbonic anhydrase I, II, VII, and IX inhibition studies with a series of benzo[d]thiazole-5- and 6-sulfonamides
por: Abdoli, Morteza, et al.
Publicado: (2017)

Psychoactive substances belonging to the amphetamine class potently activate brain carbonic anhydrase isoforms VA, VB, VII, and XII
por: Angeli, Andrea, et al.
Publicado: (2017)

Organoruthenium(II) complexes of acetazolamide potently inhibit human carbonic anhydrase isoforms I, II, IX and XII
por: Seršen, Sara, et al.
Publicado: (2019)

Sulphonamide inhibition profile of Staphylococcus aureus β-carbonic anhydrase
por: Urbanski, Linda J., et al.
Publicado: (2020)

(Hetero)aryl substituted thiazol-2,4-yl scaffold as human carbonic anhydrase I, II, VII and XIV activators
por: Rami, Marouan, et al.
Publicado: (2019)

4-(3-Alkyl/benzyl-guanidino)benzenesulfonamides as selective carbonic anhydrase VII inhibitors
por: Abdoli, Morteza, et al.
Publicado: (2022)

Activation of the β-carbonic anhydrase from the protozoan pathogen Trichomonas vaginalis with amines and amino acids
por: Angeli, Andrea, et al.
Publicado: (2021)

Click chemistry approaches for developing carbonic anhydrase inhibitors and their applications
por: Angeli, Andrea, et al.
Publicado: (2023)

Screening of benzenesulfonamide in combination with chemically diverse fragments against carbonic anhydrase by differential scanning fluorimetry
por: Krasavin, Mikhail, et al.
Publicado: (2019)

Biological investigation of N-methyl thiosemicarbazones as antimicrobial agents and bacterial carbonic anhydrases inhibitors
por: D’Agostino, Ilaria, et al.
Publicado: (2022)

Novel sulphonamides incorporating triazene moieties show powerful carbonic anhydrase I and II inhibitory properties
por: Bilginer, Sinan, et al.
Publicado: (2019)

Inhibition of the β-carbonic anhydrase from the protozoan pathogen Trichomonas vaginalis with sulphonamides
por: Urbański, Linda J., et al.
Publicado: (2020)

Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII
por: Fiorentino, Francesco, et al.
Publicado: (2023)

Activation of carbonic anhydrases from human brain by amino alcohol oxime ethers: towards human carbonic anhydrase VII selective activators
por: Nocentini, Alessio, et al.
Publicado: (2020)

New Dual P-Glycoprotein (P-gp) and Human Carbonic Anhydrase XII (hCA XII) Inhibitors as Multidrug Resistance (MDR) Reversers in Cancer Cells
por: Braconi, Laura, et al.
Publicado: (2022)

Inhibition of bacterial α-, β- and γ-class carbonic anhydrases with selenazoles incorporating benzenesulfonamide moieties
por: Angeli, Andrea, et al.
Publicado: (2018)

Synthesis of a new series of 3-functionalised-1-phenyl-1,2,3-triazole sulfamoylbenzamides as carbonic anhydrase I, II, IV and IX inhibitors
por: Swain, Baijayantimala, et al.
Publicado: (2019)

Carbonic Anhydrases and Metabolism
por: Supuran, Claudiu T.
Publicado: (2018)

Fluoroenesulphonamides: N-sulphonylurea isosteres showing nanomolar selective cancer-related transmembrane human carbonic anhydrase inhibition
por: Métayer, Benoit, et al.
Publicado: (2018)

Carbonic Anhydrase Inhibitors. Part 55(1) Metal Complexes of 1,3,4-Thiadiazole-2-Sulfonamide Derivatives: In Vitro Inhibition Studies With Carbonic Anhydrase Isozymes I, II and IV
por: Supuran, Claudiu T., et al.
Publicado: (1998)

Diversely substituted sulfamides for fragment-based drug discovery of carbonic anhydrase inhibitors: synthesis and inhibitory profile
por: Sharonova, Tatiana, et al.
Publicado: (2022)

Diversely N-substituted benzenesulfonamides dissimilarly bind to human carbonic anhydrases: crystallographic investigations of N-nitrosulfonamides
por: Angeli, Andrea, et al.
Publicado: (2023)

Carbonic Anhydrase Activators. Part 19(1) Spectroscopic and Kinetic Investigations for the Interaction of Isozymes I and II With Primary Amines
por: Briganti, Fabrizio, et al.
Publicado: (1997)

Insights into the role of reactive sulfhydryl groups of Carbonic Anhydrase III and VII during oxidative damage
por: Monti, Daria M., et al.
Publicado: (2016)

Novel 1,3,5-Triazinyl Aminobenzenesulfonamides Incorporating Aminoalcohol, Aminochalcone and Aminostilbene Structural Motifs as Potent Anti-VRE Agents, and Carbonic Anhydrases I, II, VII, IX, and XII Inhibitors
por: Havránková, Eva, et al.
Publicado: (2021)

A class of carbonic anhydrase IX/XII – selective carboxylate inhibitors
por: Alhameed, Rakia Abd, et al.
Publicado: (2020)

2-((1H-Benzo[d]imidazol-2-yl)amino)benzo[d]thiazole-6-sulphonamides: a class of carbonic anhydrase II and VII-selective inhibitors
por: Abdoli, Morteza, et al.
Publicado: (2023)

Inhibition of α-, β-, γ-, δ-, ζ- and η-class carbonic anhydrases from bacteria, fungi, algae, diatoms and protozoans with famotidine
por: Angeli, Andrea, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_hjkk8pdi1q4o08j2dsb20cothp