Zinc binding groups for histone deacetylase inhibitors

Zinc binding groups (ZBGs) play a crucial role in targeting histone deacetylase inhibitors (HDACIs) to the active site of histone deacetylases (HDACs), thus determining the potency of HDACIs. Due to the high affinity to the zinc ion, hydroxamic acid is the most commonly used ZBG in the structure of...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Zhang, Jian, Jiang, Qixiao, Zhang, Li, Song, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009916/
https://www.ncbi.nlm.nih.gov/pubmed/29616828
http://dx.doi.org/10.1080/14756366.2017.1417274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009916/
https://www.ncbi.nlm.nih.gov/pubmed/29616828
http://dx.doi.org/10.1080/14756366.2017.1417274

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