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Carbon- versus sulphur-based zinc binding groups for carbonic anhydrase inhibitors?

A set of compounds incorporating carbon-based zinc-binding groups (ZBGs), of the type PhX (X = COOH, CONH(2), CONHNH(2), CONHOH, CONHOMe), and the corresponding derivatives with sulphur(VI)-based ZBGs (X = SO(3)H, SO(2)NH(2), SO(2)NHNH(2), SO(2)NHOH, SO(2)NHOMe) were tested as inhibitors of all mamm...

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Detalles Bibliográficos
Autor principal: Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009921/
https://www.ncbi.nlm.nih.gov/pubmed/29390912
http://dx.doi.org/10.1080/14756366.2018.1428572