One-pot three-component synthesis of novel spirooxindoles with potential cytotoxic activity against triple-negative breast cancer MDA-MB-231 cells

Triple-negative breast cancer (TNBC) is a highly aggressive malignancy with limited treatment options due to its heterogeneity and the lack of well-defined molecular targets. In our endeavour towards the development of novel anti-TNBC agents, herein we report a one-pot three-component synthesis of n...

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Detalles Bibliográficos
Autores principales: Eldehna, Wagdy M., EL-Naggar, Dina H., Hamed, Ahmed R., Ibrahim, Hany S., Ghabbour, Hazem A., Abdel-Aziz, Hatem A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009943/
https://www.ncbi.nlm.nih.gov/pubmed/29281924
http://dx.doi.org/10.1080/14756366.2017.1417276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009943/
https://www.ncbi.nlm.nih.gov/pubmed/29281924
http://dx.doi.org/10.1080/14756366.2017.1417276

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