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One-pot three-component synthesis of novel spirooxindoles with potential cytotoxic activity against triple-negative breast cancer MDA-MB-231 cells
Triple-negative breast cancer (TNBC) is a highly aggressive malignancy with limited treatment options due to its heterogeneity and the lack of well-defined molecular targets. In our endeavour towards the development of novel anti-TNBC agents, herein we report a one-pot three-component synthesis of n...
Autores principales: | Eldehna, Wagdy M., EL-Naggar, Dina H., Hamed, Ahmed R., Ibrahim, Hany S., Ghabbour, Hazem A., Abdel-Aziz, Hatem A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009943/ https://www.ncbi.nlm.nih.gov/pubmed/29281924 http://dx.doi.org/10.1080/14756366.2017.1417276 |
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