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Synthesis and characterisation of celastrol derivatives as potential anticancer agents

In the present study, three series of novel celastrol derivatives were designed and synthesised by modifying the carboxylic acid at the 20th position with amino acid, amine, and triazole derivatives. All the synthesised compounds were screened for their anticancer activities using MTT assay against...

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Detalles Bibliográficos
Autores principales: Zhang, Hong-Jian, Zhang, Guo-Rui, Piao, Hu-Ri, Quan, Zhe-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009949/
https://www.ncbi.nlm.nih.gov/pubmed/29231066
http://dx.doi.org/10.1080/14756366.2017.1404590