Synthesis of new pyridothienopyrimidinone and pyridothienotriazolopyrimidine derivatives as pim-1 inhibitors

Three series of 2-arylpyridothieno[3,2-d]pyrimidin-4-ones 3a–j, pyridothienotriazolopyrimidines 6–8 and 4-imino-pyridothieno[3,2-d]pyrimidines 9a,b were prepared to improve the pim-1 inhibitory activity of the previously reported 2-arylpyridothieno[3,2-d]pyrimidin-4-ones. All the test compounds show...

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Detalles Bibliográficos
Autores principales: El-Nassan, Hala B., Naguib, Bassem H., Beshay, Engy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009955/
https://www.ncbi.nlm.nih.gov/pubmed/29161928
http://dx.doi.org/10.1080/14756366.2017.1389921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009955/
https://www.ncbi.nlm.nih.gov/pubmed/29161928
http://dx.doi.org/10.1080/14756366.2017.1389921

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