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Maintenance of memory-type pathogenic Th2 cells in the pathophysiology of chronic airway inflammation

BACKGROUND: Immunological memory is critical for long-standing protection against microorganisms; however, certain antigen-specific memory CD4(+) T helper (Th) cells drive immune-related pathology, including chronic allergic inflammation such as asthma. The IL-5-producing memory-type Tpath2 subset i...

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Detalles Bibliográficos
Autores principales: Hirahara, Kiyoshi, Shinoda, Kenta, Endo, Yusuke, Ichikawa, Tomomi, Nakayama, Toshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009957/
https://www.ncbi.nlm.nih.gov/pubmed/29951134
http://dx.doi.org/10.1186/s41232-018-0067-8