Identification of cisplatin-binding sites on the large cytoplasmic loop of the Na(+)/K(+)-ATPase

Cisplatin is the most widely used chemotherapeutic drug for the treatment of various types of cancer; however, its administration brings also numerous side effects. It was demonstrated that cisplatin can inhibit the Na(+)/K(+)-ATPase (NKA), which can explain a large part of the adverse effects. In t...

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Detalles Bibliográficos
Autores principales: Šeflová, Jaroslava, Čechová, Petra, Štenclová, Tereza, Šebela, Marek, Kubala, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009960/
https://www.ncbi.nlm.nih.gov/pubmed/29577756
http://dx.doi.org/10.1080/14756366.2018.1445735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009960/
https://www.ncbi.nlm.nih.gov/pubmed/29577756
http://dx.doi.org/10.1080/14756366.2018.1445735

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