Cargando…
Identification of cisplatin-binding sites on the large cytoplasmic loop of the Na(+)/K(+)-ATPase
Cisplatin is the most widely used chemotherapeutic drug for the treatment of various types of cancer; however, its administration brings also numerous side effects. It was demonstrated that cisplatin can inhibit the Na(+)/K(+)-ATPase (NKA), which can explain a large part of the adverse effects. In t...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009960/ https://www.ncbi.nlm.nih.gov/pubmed/29577756 http://dx.doi.org/10.1080/14756366.2018.1445735 |