Cargando…

Novel 1-(2-pyrimidin-2-yl)piperazine derivatives as selective monoamine oxidase (MAO)-A inhibitors

In the present study, a new series of 2-[4-(pyrimidin-2-yl)piperazin-1-yl]-2-oxoethyl 4-substituted piperazine-1-carbodithioate derivatives (2a-n) were synthesized and screened for their monoamine oxidase A and B inhibitory activity. The structures of compounds were elucidated using spectroscopic me...

Descripción completa

Detalles Bibliográficos
Autores principales: Kaya, Betül, Yurttaş, Leyla, Sağlik, Begüm Nurpelin, Levent, Serkan, Özkay, Yusuf, Kaplancikli, Zafer Asim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009961/
https://www.ncbi.nlm.nih.gov/pubmed/28097890
http://dx.doi.org/10.1080/14756366.2016.1247054