Diaryl ethers with carboxymethoxyphenacyl motif as potent HIV-1 reverse transcriptase inhibitors with improved solubility

In search of new non-nucleoside reverse transcriptase inhibitors (NNRTIs) with improved solubility, two series of novel diaryl ethers with phenacyl moiety were designed and evaluated for their HIV-1 reverse transcriptase inhibition potentials. All compounds exhibited good to excellent results with I...

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Detalles Bibliográficos
Autores principales: Frączek, Tomasz, Kamiński, Rafał, Krakowiak, Agnieszka, Naessens, Evelien, Verhasselt, Bruno, Paneth, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009982/
https://www.ncbi.nlm.nih.gov/pubmed/29098886
http://dx.doi.org/10.1080/14756366.2017.1387542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009982/
https://www.ncbi.nlm.nih.gov/pubmed/29098886
http://dx.doi.org/10.1080/14756366.2017.1387542

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