Synthesis and biological evaluation of alpha-bromoacryloylamido indolyl pyridinyl propenones as potent apoptotic inducers in human leukaemia cells

The combination of two pharmacophores into a single molecule represents one of the methods that can be adopted for the synthesis of new anticancer molecules. To investigate the influence of the position of the pyridine nitrogen on biological activity, two different series of α-bromoacryloylamido ind...

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Detalles Bibliográficos
Autores principales: Romagnoli, Romeo, Prencipe, Filippo, Lopez-Cara, Luisa Carlota, Oliva, Paola, Baraldi, Stefania, Baraldi, Pier Giovanni, Estévez-Sarmiento, Francisco, Quintana, José, Estévez, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009983/
https://www.ncbi.nlm.nih.gov/pubmed/29620429
http://dx.doi.org/10.1080/14756366.2018.1450749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009983/
https://www.ncbi.nlm.nih.gov/pubmed/29620429
http://dx.doi.org/10.1080/14756366.2018.1450749

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