Structure–activity relationship investigation of benzamide and picolinamide derivatives containing dimethylamine side chain as acetylcholinesterase inhibitors

A series of benzamide and picolinamide derivatives containing dimethylamine side chain (4a–4c and 7a–7i) were synthesised and evaluated for acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activity in vitro. Structure–activity relationship investigation revealed that the subst...

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Detalles Bibliográficos
Autores principales: Gao, Xiao-hui, Liu, Lin-bo, Liu, Hao-ran, Tang, Jing-jing, Kang, Lu, Wu, Hongnian, Cui, Peiwu, Yan, Jianye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009985/
https://www.ncbi.nlm.nih.gov/pubmed/29166796
http://dx.doi.org/10.1080/14756366.2017.1399885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009985/
https://www.ncbi.nlm.nih.gov/pubmed/29166796
http://dx.doi.org/10.1080/14756366.2017.1399885

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