Synthesis, pharmacology and molecular docking on multifunctional tacrine-ferulic acid hybrids as cholinesterase inhibitors against Alzheimer’s disease

The cholinergic hypothesis has long been a “polar star” in drug discovery for Alzheimer’s disease (AD), resulting in many small molecules and biological drug candidates. Most of the drugs marketed for AD are cholinergic. Herein, we report our efforts in the discovery of cholinesterases inhibitors (C...

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Detalles Bibliográficos
Autores principales: Zhu, Jie, Yang, Hongyu, Chen, Yao, Lin, Hongzhi, Li, Qi, Mo, Jun, Bian, Yaoyao, Pei, Yuqiong, Sun, Haopeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010002/
https://www.ncbi.nlm.nih.gov/pubmed/29405075
http://dx.doi.org/10.1080/14756366.2018.1430691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010002/
https://www.ncbi.nlm.nih.gov/pubmed/29405075
http://dx.doi.org/10.1080/14756366.2018.1430691

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