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Acute leukemia cells resistant to PI3K/mTOR inhibition display upregulation of P2RY14 expression
The PI3K/mTOR pathway is the second most frequently deregulated pathway in a majority of cancers such as breast cancer, lung cancer, and melanomas as well as leukemia. Mutations in the genes coding for receptor tyrosine kinases (RTKs) and G-protein-coupled receptors (GPCRs) are quite common in all f...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010022/ https://www.ncbi.nlm.nih.gov/pubmed/29951132 http://dx.doi.org/10.1186/s13148-018-0516-x |