Diethylalkylsulfonamido(4-methoxyphenyl)methyl)phosphonate/phosphonic acid derivatives act as acid phosphatase inhibitors: synthesis accompanied by experimental and molecular modeling assessments

Purple acid phosphatases (PAPs) are binuclear metallo-hydrolases that have been isolated from various mammals, plants, fungi and bacteria. In mammals, PAP activity is associated with bone resorption and can lead to bone metabolic disorders such as osteoporosis; thus human PAP is an attractive target...

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Detalles Bibliográficos
Autores principales: Alimoradi, Nahid, Ashrafi-Kooshk, Mohammad Reza, Shahlaei, Mohsen, Maghsoudi, Shabnam, Adibi, Hadi, McGeary, Ross P., Khodarahmi, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010023/
https://www.ncbi.nlm.nih.gov/pubmed/27766897
http://dx.doi.org/10.1080/14756366.2016.1230109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010023/
https://www.ncbi.nlm.nih.gov/pubmed/27766897
http://dx.doi.org/10.1080/14756366.2016.1230109

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