Cargando…

Iodine-mediated one-pot intramolecular decarboxylation domino reaction for accessing functionalised 2-(1,3,4-oxadiazol-2-yl)anilines with carbonic anhydrase inhibitory action

A practical and transition metal-free one-pot domino synthesis of diversified (1,3,4-oxadiazol-2-yl)anilines has been developed employing isatins and hydrazides as the starting materials, in the presence of molecular iodine. The prominent feature of this domino process involves consecutive condensat...

Descripción completa

Detalles Bibliográficos
Autores principales: Angapelly, Srinivas, Ramya, P. V. Sri, Sodhi, Rohini, Angeli, Andrea, Rangan, Krishnan, Nagesh, Narayana, Supuran, Claudiu T., Arifuddin, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010027/
https://www.ncbi.nlm.nih.gov/pubmed/29536768
http://dx.doi.org/10.1080/14756366.2018.1443447