Type 2 diabetes and cardiometabolic risk may be associated with increase in DNA methylation of FKBP5

BACKGROUND: Subclinical hypercortisolism and hypothalamic-pituitary-adrenal (HPA) axis dysfunction are associated with type 2 diabetes (T2DM), cardiovascular disease, and metabolic dysfunction. Intronic methylation of FKBP5 has been implicated as a potential indicator of chronic cortisol exposure. O...

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Detalles Bibliográficos
Autores principales: Ortiz, Robin, Joseph, Joshua J., Lee, Richard, Wand, Gary S., Golden, Sherita Hill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010037/
https://www.ncbi.nlm.nih.gov/pubmed/29951131
http://dx.doi.org/10.1186/s13148-018-0513-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010037/
https://www.ncbi.nlm.nih.gov/pubmed/29951131
http://dx.doi.org/10.1186/s13148-018-0513-0

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