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Type 2 diabetes and cardiometabolic risk may be associated with increase in DNA methylation of FKBP5
BACKGROUND: Subclinical hypercortisolism and hypothalamic-pituitary-adrenal (HPA) axis dysfunction are associated with type 2 diabetes (T2DM), cardiovascular disease, and metabolic dysfunction. Intronic methylation of FKBP5 has been implicated as a potential indicator of chronic cortisol exposure. O...
Autores principales: | Ortiz, Robin, Joseph, Joshua J., Lee, Richard, Wand, Gary S., Golden, Sherita Hill |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010037/ https://www.ncbi.nlm.nih.gov/pubmed/29951131 http://dx.doi.org/10.1186/s13148-018-0513-0 |
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