The hop-derived compounds xanthohumol, isoxanthohumol and 8-prenylnaringenin are tight-binding inhibitors of human aldo-keto reductases 1B1 and 1B10

Xanthohumol (XN), a prenylated chalcone unique to hops (Humulus lupulus) and two derived prenylflavanones, isoxanthohumol (IX) and 8-prenylnaringenin (8-PN) gained increasing attention as potential anti-diabetic and cancer preventive compounds. Two enzymes of the aldo-keto reductase (AKR) superfamil...

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Detalles Bibliográficos
Autores principales: Seliger, Jan Moritz, Misuri, Livia, Maser, Edmund, Hintzpeter, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010053/
https://www.ncbi.nlm.nih.gov/pubmed/29532688
http://dx.doi.org/10.1080/14756366.2018.1437728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010053/
https://www.ncbi.nlm.nih.gov/pubmed/29532688
http://dx.doi.org/10.1080/14756366.2018.1437728

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