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The RFK catalytic cycle of the pathogen Streptococcus pneumoniae shows species-specific features in prokaryotic FMN synthesis

Emergence of multidrug-resistant bacteria forces us to explore new therapeutic strategies, and proteins involved in key metabolic pathways are promising anti-bacterial targets. Bifunctional flavin-adenine dinucleotide (FAD) synthetases (FADS) are prokaryotic enzymes that synthesise the flavin mononu...

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Detalles Bibliográficos
Autores principales: Sebastián, María, Velázquez-Campoy, Adrián, Medina, Milagros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010069/
https://www.ncbi.nlm.nih.gov/pubmed/29693467
http://dx.doi.org/10.1080/14756366.2018.1461857