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A class of carbonic anhydrase I – selective activators

A series of ureido and bis-ureido derivatives were prepared by reacting histamine with alkyl/aryl-isocyanates or di-isocyanates. The obtained derivatives were assayed as activators of the enzyme carbonic anhydrase (CA, EC 4.2.1.1), due to the fact that histamine itself has this biological activity....

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Detalles Bibliográficos
Autores principales: Licsandru, Erol, Tanc, Muhammet, Kocsis, Istvan, Barboiu, Mihail, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010081/
https://www.ncbi.nlm.nih.gov/pubmed/27798977
http://dx.doi.org/10.1080/14756366.2016.1232254