Advances in the discovery of cathepsin K inhibitors on bone resorption

Cathepsin K (Cat K), highly expressed in osteoclasts, is a cysteine protease member of the cathepsin lysosomal protease family and has been of increasing interest as a target of medicinal chemistry efforts for its role in bone matrix degradation. Inhibition of the Cat K enzyme reduces bone resorptio...

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Detalles Bibliográficos
Autores principales: Lu, Jun, Wang, Maolin, Wang, Ziyue, Fu, Zhongqi, Lu, Aiping, Zhang, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010086/
https://www.ncbi.nlm.nih.gov/pubmed/29723068
http://dx.doi.org/10.1080/14756366.2018.1465417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010086/
https://www.ncbi.nlm.nih.gov/pubmed/29723068
http://dx.doi.org/10.1080/14756366.2018.1465417

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