Novel hits for acetylcholinesterase inhibition derived by docking-based screening on ZINC database

The inhibition of the enzyme acetylcholinesterase (AChE) increases the levels of the neurotransmitter acetylcholine and symptomatically improves the affected cognitive function. In the present study, we searched for novel AChE inhibitors by docking-based virtual screening of the standard lead-like s...

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Detalles Bibliográficos
Autores principales: Doytchinova, Irini, Atanasova, Mariyana, Valkova, Iva, Stavrakov, Georgi, Philipova, Irena, Zhivkova, Zvetanka, Zheleva-Dimitrova, Dimitrina, Konstantinov, Spiro, Dimitrov, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010092/
https://www.ncbi.nlm.nih.gov/pubmed/29651876
http://dx.doi.org/10.1080/14756366.2018.1458031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010092/
https://www.ncbi.nlm.nih.gov/pubmed/29651876
http://dx.doi.org/10.1080/14756366.2018.1458031

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