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Dioxygen, an unexpected carbonic anhydrase ligand

Carbonic anhydrases (CAs, EC 4.2.1.1) are ubiquitous metalloenzymes, grouped into seven different classes, which catalyze the reaction of CO(2) hydration to bicarbonate and protons. All of the fifteen human isoforms reported to date belong to the α-class and contain zinc as a cofactor. The structure...

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Detalles Bibliográficos
Autores principales: Ferraroni, Marta, Gaspari, Roberto, Scozzafava, Andrea, Cavalli, Andrea, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010096/
https://www.ncbi.nlm.nih.gov/pubmed/29806484
http://dx.doi.org/10.1080/14756366.2018.1475371