A mechanistic kinetic description of lactate dehydrogenase elucidating cancer diagnosis and inhibitor evaluation

As a key enzyme for glycolysis, lactate dehydrogenase (LDH) remains as a topic of great interest in cancer study. Though a number of kinetic models have been applied to describe the dynamic behavior of LDH, few can reflect its actual mechanism, making it difficult to explain the observed substrate a...

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Detalles Bibliográficos
Autores principales: Tang, Peifeng, Xu, Jianlin, Oliveira, Christopher L., Li, Zheng Jian, Liu, Shijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010104/
https://www.ncbi.nlm.nih.gov/pubmed/28114833
http://dx.doi.org/10.1080/14756366.2016.1275606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010104/
https://www.ncbi.nlm.nih.gov/pubmed/28114833
http://dx.doi.org/10.1080/14756366.2016.1275606

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