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A mechanistic kinetic description of lactate dehydrogenase elucidating cancer diagnosis and inhibitor evaluation
As a key enzyme for glycolysis, lactate dehydrogenase (LDH) remains as a topic of great interest in cancer study. Though a number of kinetic models have been applied to describe the dynamic behavior of LDH, few can reflect its actual mechanism, making it difficult to explain the observed substrate a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010104/ https://www.ncbi.nlm.nih.gov/pubmed/28114833 http://dx.doi.org/10.1080/14756366.2016.1275606 |