Synthesis, biological evaluation and molecular modeling studies on novel quinonoid inhibitors of CDC25 phosphatases

The cell division cycle 25 phosphatases (CDC25A, B, and C; E.C. 3.1.3.48) are key regulator of the cell cycle in human cells. Their aberrant expression has been associated with the insurgence and development of various types of cancer, and with a poor clinical prognosis. Therefore, CDC25 phosphatase...

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Detalles Bibliográficos
Autores principales: Evain-Bana, Emilie, Schiavo, Lucie, Bour, Christophe, Lanfranchi, Don Antoine, Berardozzi, Simone, Ghirga, Francesca, Bagrel, Denyse, Botta, Bruno, Hanquet, Gilles, Mori, Mattia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010111/
https://www.ncbi.nlm.nih.gov/pubmed/27774816
http://dx.doi.org/10.1080/14756366.2016.1238364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010111/
https://www.ncbi.nlm.nih.gov/pubmed/27774816
http://dx.doi.org/10.1080/14756366.2016.1238364

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