Resolution of co-eluting isomers of anti-inflammatory drugs conjugated to carbonic anhydrase inhibitors from plasma in liquid chromatography by energy-resolved tandem mass spectrometry

Rheumatoid arthritis (RA) is a chronic inflammatory disease caused by a faulty autoimmune response. Recently, it was reported that some human carbonic anhydrases (CAs) isoforms are overexpressed in inflamed synovium of RA patients. New CA inhibitors (CAIs) incorporating CA-binding moiety and the cyc...

Descripción completa

Detalles Bibliográficos
Autores principales: Menicatti, Marta, Pallecchi, Marco, Bua, Silvia, Vullo, Daniela, Di Cesare Mannelli, Lorenzo, Ghelardini, Carla, Carta, Fabrizio, Supuran, Claudiu T., Bartolucci, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010112/
https://www.ncbi.nlm.nih.gov/pubmed/29536775
http://dx.doi.org/10.1080/14756366.2018.1445737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010112/
https://www.ncbi.nlm.nih.gov/pubmed/29536775
http://dx.doi.org/10.1080/14756366.2018.1445737

Ejemplares similares