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Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors

The isatin scaffold is the constitutive fragment of several natural and synthetic bioactive molecules. Albeit several benzene sulphonamide-based carbonic anhydrase inhibitors (CAIs) have been reported, only recently isatin benzene sulphonamides have been studied and proposed as CAIs. In this study w...

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Detalles Bibliográficos
Autores principales: Melis, Claudia, Meleddu, Rita, Angeli, Andrea, Distinto, Simona, Bianco, Giulia, Capasso, Clemente, Cottiglia, Filippo, Angius, Rossella, Supuran, Claudiu T., Maccioni, Elias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010117/
https://www.ncbi.nlm.nih.gov/pubmed/27775452
http://dx.doi.org/10.1080/14756366.2016.1235042