Synthesis and biological evaluation of histamine Schiff bases as carbonic anhydrase I, II, IV, VII, and IX activators

A series of 20 histamine Schiff base was synthesised by reaction of histamine, a well known carbonic anhydrase (CA, E.C 4.2.2.1.) activator pharmacophore, with substituted aldehydes. The obtained histamine Schiff bases were assayed as activators of five selected human (h) CA isozymes, the cytosolic...

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Detalles Bibliográficos
Autores principales: Akocak, Suleyman, Lolak, Nabih, Vullo, Daniela, Durgun, Mustafa, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010137/
https://www.ncbi.nlm.nih.gov/pubmed/29072105
http://dx.doi.org/10.1080/14756366.2017.1386660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010137/
https://www.ncbi.nlm.nih.gov/pubmed/29072105
http://dx.doi.org/10.1080/14756366.2017.1386660

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