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A comparison of LKB1/AMPK/mTOR metabolic axis response to global ischaemia in brain, heart, liver and kidney in a rat model of cardiac arrest

BACKGROUND: Cellular energy failure in high metabolic rate organs is one of the underlying causes for many disorders such as neurodegenerative diseases, cardiomyopathies, liver and renal failures. In the past decade, numerous studies have discovered the cellular axis of LKB1/AMPK/mTOR as an essentia...

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Detalles Bibliográficos
Autores principales: Majd, Shohreh, Power, John H. T., Chataway, Timothy K., Grantham, Hugh J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010165/
https://www.ncbi.nlm.nih.gov/pubmed/29921218
http://dx.doi.org/10.1186/s12860-018-0159-y