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In silico and ex vivo approaches indicate immune pressure on capsid and non-capsid regions of coxsackie B viruses in the human system

Coxsackie B Virus (CBV) infection has been linked to the aetiology of type 1 diabetes (T1D) and vaccination has been proposed as prophylaxis for disease prevention. Serum neutralising antibodies and the presence of viral protein and RNA in tissues have been common tools to examine this potential dis...

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Detalles Bibliográficos
Autores principales: Kundu, Rhiannon, Knight, Robin, Dunga, Meenakshi, Peakman, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010236/
https://www.ncbi.nlm.nih.gov/pubmed/29924875
http://dx.doi.org/10.1371/journal.pone.0199323