TWEAK increases CD74 expression and sensitizes to DDT proinflammatory actions in tubular cells

CD74 is a multifunctional protein and a receptor for Macrophage Migration Inhibitory Factor (MIF) and MIF-2 / D-dopachrome tautomerase (DDT) cytokines, upregulated in diabetic kidney disease. However, the drivers of CD74 expression and DDT function in kidney cells are poorly characterized. TWEAK is...

Descripción completa

Detalles Bibliográficos
Autores principales: Valiño-Rivas, Lara, Cuarental, Leticia, Grana, Osvaldo, Bucala, Richard, Leng, Lin, Sanz, Ana, Gomez, Gonzalo, Ortiz, Alberto, Sanchez-Niño, Maria Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010292/
https://www.ncbi.nlm.nih.gov/pubmed/29924850
http://dx.doi.org/10.1371/journal.pone.0199391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010292/
https://www.ncbi.nlm.nih.gov/pubmed/29924850
http://dx.doi.org/10.1371/journal.pone.0199391

Ejemplares similares