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Immunity drives TET1 regulation in cancer through NF-κB

Ten-eleven translocation enzymes (TET1, TET2, and TET3), which induce DNA demethylation and gene regulation by converting 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), are often down-regulated in cancer. We uncover, in basal-like breast cancer (BLBC), genome-wide 5hmC changes related to...

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Detalles Bibliográficos
Autores principales: Collignon, Evelyne, Canale, Annalisa, Al Wardi, Clémence, Bizet, Martin, Calonne, Emilie, Dedeurwaerder, Sarah, Garaud, Soizic, Naveaux, Céline, Barham, Whitney, Wilson, Andrew, Bouchat, Sophie, Hubert, Pascale, Van Lint, Carine, Yull, Fiona, Sotiriou, Christos, Willard-Gallo, Karen, Noel, Agnès, Fuks, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010319/
https://www.ncbi.nlm.nih.gov/pubmed/29938218
http://dx.doi.org/10.1126/sciadv.aap7309