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Heterogeneity of spontaneous DNA replication errors in single isogenic Escherichia coli cells

Despite extensive knowledge of the molecular mechanisms that control mutagenesis, it is not known how spontaneous mutations are produced in cells with fully operative mutation-prevention systems. By using a mutation assay that allows visualization of DNA replication errors and stress response transc...

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Detalles Bibliográficos
Autores principales: Woo, Anthony C., Faure, Louis, Dapa, Tanja, Matic, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010332/
https://www.ncbi.nlm.nih.gov/pubmed/29938224
http://dx.doi.org/10.1126/sciadv.aat1608