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A transgenic mouse for imaging activity-dependent dynamics of endogenous Arc mRNA in live neurons
Localized translation plays a crucial role in synaptic plasticity and memory consolidation. However, it has not been possible to follow the dynamics of memory-associated mRNAs in living neurons in response to neuronal activity in real time. We have generated a novel mouse model where the endogenous...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010337/ https://www.ncbi.nlm.nih.gov/pubmed/29938222 http://dx.doi.org/10.1126/sciadv.aar3448 |