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Expression of human mutant cyclin dependent kinase 4, Cyclin D and telomerase extends the life span but does not immortalize fibroblasts derived from loggerhead sea turtle (Caretta caretta)

Conservation of the genetic resources of endangered animals is crucial for future generations. The loggerhead sea turtle (Caretta caretta) is a critically endangered species, because of human hunting, hybridisation with other sea turtle species, and infectious diseases. In the present study, we esta...

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Detalles Bibliográficos
Autores principales: Fukuda, Tomokazu, Eitsuka, Takahiro, Donai, Kenichiro, Kurita, Masanori, Saito, Tomomi, Okamoto, Hitoshi, Kinoshita, Kodzue, Katayama, Masafumi, Nitto, Hiroshi, Uchida, Takafumi, Onuma, Manabu, Sone, Hideko, Inoue-Murayama, Miho, Kiyono, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010431/
https://www.ncbi.nlm.nih.gov/pubmed/29925962
http://dx.doi.org/10.1038/s41598-018-27271-x