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Further dissection of QTLs for salt-induced stroke and identification of candidate genes in the stroke-prone spontaneously hypertensive rat

We previously revealed that two major quantitative trait loci (QTLs) for stroke latency of the stroke-prone spontaneously hypertensive rat (SHRSP) under salt-loading were located on chromosome (Chr) 1 and 18. Here, we attempted further dissection of the stroke-QTLs using multiple congenic strains be...

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Detalles Bibliográficos
Autores principales: Niiya, Kaoru, Ohara, Hiroki, Isono, Masato, Sheikh, Abdullah Md., Matsuo, Hiroyuki, Fujikawa, Koichi, Isomura, Minoru, Kato, Norihiro, Nabika, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010461/
https://www.ncbi.nlm.nih.gov/pubmed/29925869
http://dx.doi.org/10.1038/s41598-018-27539-2