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Use of 5-azacytidine in a proof-of-concept study to evaluate the impact of pre-natal and post-natal exposures, as well as within generation persistent DNA methylation changes in Daphnia

Short-term exposures at critical stages of development can lead to delayed adverse effects long after the initial stressor has been removed, a concept referred to as developmental origin of adult disease. This indicates that organisms’ phenotypes may epigenetically reflect their past exposure histor...

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Detalles Bibliográficos
Autores principales: Athanasio, Camila Gonçalves, Sommer, Ulf, Viant, Mark R., Chipman, James Kevin, Mirbahai, Leda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010494/
https://www.ncbi.nlm.nih.gov/pubmed/29623456
http://dx.doi.org/10.1007/s10646-018-1927-3