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New Genetically Manipulated Mice Provide Insights Into the Development and Physiological Functions of Invariant Natural Killer T Cells

Invariant natural killer T (iNKT) cells are a unique T cell subset that exhibits characteristics of both innate immune cells and T cells. They express Vα14-Jα18 (Trav11-Traj18) as an invariant chain of the T cell receptor (TCR) and are restricted to the MHC class I-like monomorphic antigen presentin...

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Detalles Bibliográficos
Autores principales: Ren, Yue, Sekine-Kondo, Etsuko, Tateyama, Midori, Kasetthat, Thitinan, Wongratanacheewin, Surasakadi, Watarai, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010523/
https://www.ncbi.nlm.nih.gov/pubmed/29963043
http://dx.doi.org/10.3389/fimmu.2018.01294