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In Silico Approaches Applied to the Study of Peptide Analogs of Ile-Pro-Ile in Relation to Their Dipeptidyl Peptidase IV Inhibitory Properties

Inhibition of dipeptidyl peptidase IV (DPP-IV) may be exploited to maintain the incretin effect during the postprandial phase. As a result, glycemic regulation and energy homeostasis may be improved. Food protein-derived peptides have been identified as natural agents capable of inhibiting DPP-IV. I...

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Detalles Bibliográficos
Autores principales: Nongonierma, Alice B., Dellafiora, Luca, Paolella, Sara, Galaverna, Gianni, Cozzini, Pietro, FitzGerald, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010526/
https://www.ncbi.nlm.nih.gov/pubmed/29963014
http://dx.doi.org/10.3389/fendo.2018.00329