Toll-Like Receptor 4 Triggering Promotes Cytosolic Routing of DC-SIGN-Targeted Antigens for Presentation on MHC Class I

DC-SIGN is an antigen uptake receptor expressed on dendritic cells (DCs) with specificity for glycans present on a broad variety of pathogens and is capable of directing its cargo to MHC-I and MHC-II pathways for the induction of CD8(+) and CD4(+) T cell responses, respectively. Therefore, DC-SIGN i...

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Detalles Bibliográficos
Autores principales: Horrevorts, Sophie K., Duinkerken, Sanne, Bloem, Karien, Secades, Pablo, Kalay, Hakan, Musters, René J., van Vliet, Sandra J., García-Vallejo, Juan J., van Kooyk, Yvette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010527/
https://www.ncbi.nlm.nih.gov/pubmed/29963041
http://dx.doi.org/10.3389/fimmu.2018.01231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010527/
https://www.ncbi.nlm.nih.gov/pubmed/29963041
http://dx.doi.org/10.3389/fimmu.2018.01231

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