Cargando…

Toll-Like Receptor 4 Triggering Promotes Cytosolic Routing of DC-SIGN-Targeted Antigens for Presentation on MHC Class I

DC-SIGN is an antigen uptake receptor expressed on dendritic cells (DCs) with specificity for glycans present on a broad variety of pathogens and is capable of directing its cargo to MHC-I and MHC-II pathways for the induction of CD8(+) and CD4(+) T cell responses, respectively. Therefore, DC-SIGN i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Horrevorts, Sophie K., Duinkerken, Sanne, Bloem, Karien, Secades, Pablo, Kalay, Hakan, Musters, René J., van Vliet, Sandra J., García-Vallejo, Juan J., van Kooyk, Yvette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010527/ https://www.ncbi.nlm.nih.gov/pubmed/29963041 http://dx.doi.org/10.3389/fimmu.2018.01231

Ejemplares similares

Glyco-Dendrimers as Intradermal Anti-Tumor Vaccine Targeting Multiple Skin DC Subsets
por: Duinkerken, Sanne, et al.
Publicado: (2019)

The Consequences of Multiple Simultaneous C-Type Lectin–Ligand Interactions: DCIR Alters the Endo-Lysosomal Routing of DC-SIGN
por: García-Vallejo, Juan J., et al.
Publicado: (2015)

Glycan-based DC-SIGN targeting to enhance antigen cross-presentation in anticancer vaccines
por: García-Vallejo, Juan J., et al.
Publicado: (2013)

Interaction of the Capsular Polysaccharide A from Bacteroides fragilis with DC-SIGN on Human Dendritic Cells is Necessary for Its Processing and Presentation to T Cells
por: Bloem, Karien, et al.
Publicado: (2013)

Palmitoylated antigens for the induction of anti-tumor CD8(+) T cells and enhanced tumor recognition
por: Stolk, Dorian A., et al.
Publicado: (2021)

Analytical Tools for the Study of Cellular Glycosylation in the Immune System
por: van Kooyk, Yvette, et al.
Publicado: (2013)

Mouse DC-SIGN/CD209a as Target for Antigen Delivery and Adaptive Immunity
por: Schetters, Sjoerd T. T., et al.
Publicado: (2018)

Glycan modification of glioblastoma-derived extracellular vesicles enhances receptor-mediated targeting of dendritic cells
por: Dusoswa, Sophie A., et al.
Publicado: (2019)

Lipo-Based Vaccines as an Approach to Target Dendritic Cells for Induction of T- and iNKT Cell Responses
por: Stolk, Dorian A., et al.
Publicado: (2020)

Ligand Binding and Signaling of Dendritic Cell Immunoreceptor (DCIR) Is Modulated by the Glycosylation of the Carbohydrate Recognition Domain
por: Bloem, Karien, et al.
Publicado: (2013)

Activation of the C-Type Lectin MGL by Terminal GalNAc Ligands Reduces the Glycolytic Activity of Human Dendritic Cells
por: Zaal, Anouk, et al.
Publicado: (2020)

Fasciola hepatica glycoconjugates immuneregulate dendritic cells through the Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin inducing T cell anergy
por: Rodríguez, Ernesto, et al.
Publicado: (2017)

Glycan modification of antigen alters its intracellular routing in dendritic cells, promoting priming of T cells
por: Streng-Ouwehand, Ingeborg, et al.
Publicado: (2016)

Glycan-Modified Apoptotic Melanoma-Derived Extracellular Vesicles as Antigen Source for Anti-Tumor Vaccination
por: Horrevorts, Sophie K., et al.
Publicado: (2019)

Mycobacteria Target DC-SIGN to Suppress Dendritic Cell Function
por: Geijtenbeek, Teunis B.H., et al.
Publicado: (2003)

Interaction of Polysialic Acid with CCL21 Regulates the Migratory Capacity of Human Dendritic Cells
por: Bax, Marieke, et al.
Publicado: (2009)

Macrophage galactose-type lectin (MGL) is induced on M2 microglia and participates in the resolution phase of autoimmune neuroinflammation
por: Ilarregui, Juan M., et al.
Publicado: (2019)

Dysregulation of developmental and cell type-specific expression of glycoconjugates on hematopoietic cells: a new characteristic of myelodysplastic neoplasms (MDS)
por: van Spronsen, Margot F., et al.
Publicado: (2023)

Targeting Mycobacterium tuberculosis Antigens to Dendritic Cells via the DC-Specific-ICAM3-Grabbing-Nonintegrin Receptor Induces Strong T-Helper 1 Immune Responses
por: Velasquez, Lis Noelia, et al.
Publicado: (2018)

Incorporation of Toll-Like Receptor Ligands and Inflammasome Stimuli in GM3 Liposomes to Induce Dendritic Cell Maturation and T Cell Responses
por: Nijen Twilhaar, Maarten K., et al.
Publicado: (2022)

Distinct antigen uptake receptors route to the same storage compartments for cross‐presentation in dendritic cells
por: Ho, Nataschja I., et al.
Publicado: (2021)

Immunological dynamics after subcutaneous immunization with a squalene‐based oil‐in‐water adjuvant
por: Schetters, Sjoerd T. T., et al.
Publicado: (2020)

Tolerogenic Immunotherapy: Targeting DC Surface Receptors to Induce Antigen-Specific Tolerance
por: Castenmiller, Charlotte, et al.
Publicado: (2021)

α2-3 Sialic acid binding and uptake by human monocyte-derived dendritic cells alters metabolism and cytokine release and initiates tolerizing T cell programming
por: Lübbers, Joyce, et al.
Publicado: (2021)

Neutrophils mediate immune modulation of dendritic cells through glycosylation-dependent interactions between Mac-1 and DC-SIGN
por: van Gisbergen, Klaas P.J.M., et al.
Publicado: (2005)

Phenotypic and Functional Properties of Human Steady State CD14(+) and CD1a(+) Antigen Presenting Cells and Epidermal Langerhans Cells
por: Fehres, Cynthia. M., et al.
Publicado: (2015)

Human Milk Blocks DC-SIGN–Pathogen Interaction via MUC1
por: Koning, Nathalie, et al.
Publicado: (2015)

Helicobacter pylori Modulates the T Helper Cell 1/T Helper Cell 2 Balance through Phase-variable Interaction between Lipopolysaccharide and DC-SIGN
por: Bergman, Mathijs P., et al.
Publicado: (2004)

Human Milk Oligosaccharide 2′-Fucosyllactose Inhibits Ligand Binding to C-Type Lectin DC-SIGN but Not to Langerin
por: Mukherjee, Reshmi, et al.
Publicado: (2022)

Liposomal Nanovaccine Containing α-Galactosylceramide and Ganglioside GM3 Stimulates Robust CD8(+) T Cell Responses via CD169(+) Macrophages and cDC1
por: Grabowska, Joanna, et al.
Publicado: (2021)

CNS myelin induces regulatory functions of DC-SIGN–expressing, antigen-presenting cells via cognate interaction with MOG
por: García-Vallejo, J.J., et al.
Publicado: (2014)

Fucosylated Antigens in Cancer: An Alliance toward Tumor Progression, Metastasis, and Resistance to Chemotherapy
por: Blanas, Athanasios, et al.
Publicado: (2018)

Corrigendum: Fucosylated Antigens in Cancer: An Alliance Toward Tumor Progression, Metastasis, and Resistance to Chemotherapy
por: Blanas, Athanasios, et al.
Publicado: (2018)

Neuroinflammation: Microglia and T Cells Get Ready to Tango
por: Schetters, Sjoerd T. T., et al.
Publicado: (2018)

Quantitative Phosphoproteomic Analysis Reveals Dendritic Cell- Specific STAT Signaling After α2-3–Linked Sialic Acid Ligand Binding
por: Li, Rui-Jún Eveline, et al.
Publicado: (2021)

Understanding the Biology of Antigen Cross-Presentation for the Design of Vaccines Against Cancer
por: Fehres, Cynthia M., et al.
Publicado: (2014)

Skin-Resident Antigen-Presenting Cells: Instruction Manual for Vaccine Development
por: Fehres, Cynthia M., et al.
Publicado: (2013)

DC-SIGN–mediated Infectious Synapse Formation Enhances X4 HIV-1 Transmission from Dendritic Cells to T Cells
por: Arrighi, Jean-François, et al.
Publicado: (2004)

Fasciola hepatica Immune Regulates CD11c(+) Cells by Interacting with the Macrophage Gal/GalNAc Lectin
por: Rodríguez, Ernesto, et al.
Publicado: (2017)

Comparison of Protein and Peptide Targeting for the Development of a CD169-Based Vaccination Strategy Against Melanoma
por: van Dinther, Dieke, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_f2rb7hnq5jsjj2r9vkp672t98n