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Role of the Purkinje-Muscle Junction on the Ventricular Repolarization Heterogeneity in the Healthy and Ischemic Ovine Ventricular Myocardium

Alteration of action potential duration (APD) heterogeneity contributes to arrhythmogenesis. Purkinje-muscle junctions (PMJs) present differential electrophysiological properties including longer APD. The goal of this study was to determine if Purkinje-related or myocardial focal activation modulate...

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Detalles Bibliográficos
Autores principales: Martinez, Marine E., Walton, Richard D., Bayer, Jason D., Haïssaguerre, Michel, Vigmond, Edward J., Hocini, Mélèze, Bernus, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010581/
https://www.ncbi.nlm.nih.gov/pubmed/29962961
http://dx.doi.org/10.3389/fphys.2018.00718