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Bacterial RecA Protein Promotes Adenoviral Recombination during In Vitro Infection

Adenovirus infections in humans are common and sometimes lethal. Adenovirus-derived vectors are also commonly chosen for gene therapy in human clinical trials. We have shown in previous work that homologous recombination between adenoviral genomes of human adenovirus species D (HAdV-D), the largest...

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Detalles Bibliográficos
Autores principales: Lee, Jeong Yoon, Lee, Ji Sun, Materne, Emma C., Rajala, Rahul, Ismail, Ashrafali M., Seto, Donald, Dyer, David W., Rajaiya, Jaya, Chodosh, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010623/
https://www.ncbi.nlm.nih.gov/pubmed/29925671
http://dx.doi.org/10.1128/mSphere.00105-18